Optimization of Natural Rhenium Irradiation Time to Produce Compositional Radiopharmaceutical

Gamma Irradiation for Fresh Produce

Synthesis of tripeptide derivatized cyclopentadienyl complexes of technetium and rhenium as radiopharmaceutical probes.

We describe the syntheses of half-sandwich complexes of the type [(η(5)-Cp(CONH-R))M(CO)3] with M = Re or (99m)Tc. The R group represents different tri-peptides (tpe) which display high binding affinities for oligopeptide transporters PEPT2. The (99m)Tc complexes were prepared directly from [(99m)Tc(OH2)3(CO)3](+) and Diels-Alder dimerized, cyclopentadienyl derivatized peptides in water. This a...

New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents

Multiple possibilities for the coordination of fac-[Re(CO)3(H2O)3]+ to a protein have been determined and include binding to Asp, Glu, Arg and His amino-acid residues as well as to the C-terminal carboxylate in the vicinity of Leu and Pro. The large number of rhenium metal complex binding sites that have been identified on specific residues thereby allow increased target identification for the ...

Numerical study and genetic algorithm optimization of hot extrusion process to produce rectangular waveguides

Rectangular waveguide is one of the earliest types of transmission lines. Rectangular waveguide can be produced by hot extrusion process. In this paper, the hot extrusion process of CuZn5 rectangular waveguide was investigated by Finite Element Method (FEM). In addition, Genetic Algorithm (GA) was used to optimize the die geometry and process conditions to achieve the lowest magnitude of extrus...

Modeling and optimization of a natural gas pressure reduction station to produce electricity using genetic algorithm

For longer distances, natural gas is transported through transit pipeline at high pressures. In a place of consumption or at passing into a lower pressure pipeline, the pressure of the gas must be reduced. In Iran, the common procedure of reducing pressure in natural gas station is using expansion valves, which causes the waste of large amount of energy. Combined heat and power (CHP) systems ha...

Optimization of thermomechanical parameters to produce an ultra-high strength compressor disk

Structural steels with very high strength levels are often referred to as ultrahigh-strength steels (UHSS). The usage of UHSS has been extensively studied in aerospace industries and offshore platforms. In this study, medium carbon low alloy steel (AMS6305) was thermomechanicaly treated to obtain an ultra-high strength bainitic steel for aircraft engine compressor disk. A novel themomechanical ...